Fibrina rica em plaquetas e leucócitos versus plasma rico em plaquetas: propriedades e aplicação clínica

Abstract

Platelets are the main elements involved in wound healing. After coagulation, platelets granules release growth factors that initiate and support healing. Leukocyte and platelet –rich fibrin (L-PRF) is a fibrin matrix that contains leukocytes and platelets. It is obtained from recent collected blood, with no biochemical blood handling, and represents a new generation of platelet concentrates, with a simplified processing. The Platelet Rich Plasma (PRP) is a platelet concentrate obtained poscentrifugation of blood with anticoagulant. The aim of this study was to clarify some differences between L-PRF fibrin mash and PRP and find scientific evidences to support L-PRF ́s different clinical indications, through a study review. Finally, both platelet concentrates are completely different. PRP releases growth factors massively in the first hours and it is quickly dissolved from the site. L-PRF can be an excellent tool improving wound healing, promoting protection and modulating inflammatory response.