Canabidiol (CBD) no cuidado ao usuário de cocaína e/ ou crack: uma revisão narrativa

Abstract

The prevalence of cocaine and crack use, both globally and in Brazil, emerges as a public health problem for which the solution requires therapeutic strategies appropriate to the context of harm reduction. Considering that there is no approved pharmacological therapy for the treatment of cocaine use disorder (CUD) and perceiving cannabidiol (CBD) as a possible alternative, the objective of this work is to carry out a narrative review of the scientific literature on the use of CBD in treatment of TUC, in addition to the report of a specific case of a patient treated at the Centro de Atenção Psicossocial Álcool e Drogas (CAPS AD) due to cocaine use disorder (TUC) and, later, at the Drug Abuse Research and Assistance Program (PROJAD) motivated by the use of marijuana as a strategy to give up cocaine. The review was prepared in the PUBMED database, considering original works available in full online in Portuguese and English, published in the past five years and retrieved according to the following search strategy: ((CBD OR Cannabidiol OR Marijuana OR Endocannabinoids OR Cannabis Sativa) AND (Cocaine OR Crack OR Cocaine- Related Disorders OR Disorders Related on Cocaine)) AND (Treatment OR Terapia OR Therapy). Of the 537 articles reached, four were selected to compose the present work. The results revealed that, although CBD has been considered a promising alternative in some studies, it is not indicated as a treatment for patients with severe TUC. This finding highlights the importance of seeking and developing effective therapeutic approaches for TUC, given its complex nature and the challenges associated with treatment, in order to achieve improved outcomes and quality of life for individuals affected by TUC.