Perfil epidemiológico de pacientes com gliomas de alto grau em um hospital geral do Rio de Janeiro

Abstract

Purpose. Correlate the epidemiological profile of patients undergoing resection of high-grade gliomas in a general hospital in Rio Janeiro with the application of adjuvant therapy and clinical outcome. Materials and methods. A retrospective cross-sectional study was carried out on patients undergoing exeresis of expansive processes in a military hospital in Rio de Janeiro from 2012 to 2019. Results. The average age ranged from 21 to 83 years, with an average of 48.8 years in men and 59.6 years in women. The most prevalent diagnosis was glioblastoma, 75% of cases. The main location was the frontal lobes (36.11%). The overall survival in men was 528.3 days and 130.7 days in women. The overall survival in those not undergoing adjuvant therapy was 62.4 days, only radiotherapy 121.7 days and in combination therapy (chemotherapy and radiotherapy) it was 633 days. Conclusion. Combination therapy showed better results stressing the importance to case selectable methods. The approach of modifiable factors can improve the prognosis and provide a more accurate and early diagnosis. New longitudinal studies in this population are needed to interpret the data in care.